Clicking the new "Apply" button changes focus to the "Profile Name" textbox, which is different from the default window-opening behavior(which in turn seems off as well):
When initially opening the "Edit a Profile" window, focus appears to be on the command list(as using Shift-Tab jumps to the "Delete" button, and Tab subsequently focuses the list), yet the list cannot be scrolled using the mouse wheel, nor will the arrow keys affect the list initially(arrow up jumps to the "Delete" button, arrow down to the "Import Commands" button); Pressing enter does open the command that appears to be selected(as it's highlighted in blue) for editing(after closing the "Edit a Command" dialog, the list is now scrollable, as it would be when clicking inside the list as well).
Perhaps focus needs to be on an element inside the list for scrolling to work?
I checked a version back to v1.6.9.2, and to v1.6.9, and the list focus is not a new issue. Guess I'm just used to clicking it first.