Press F1 while VoiceAttack has focus to open VoiceAttackHelp.pdf in your default PDF viewer, which contains information on VoiceAttack's features.
Command-level targeting is intended to override profile-level targeting. In most circumstances you'd want to use the latter.
Commands can be multi-edited, including targeting settings.
Targeting can be done using wildcards to account for changing window titles. Targeting can also be performed using a process name, which would then not be dependent on a window title.