Hi, Jim
What you can do is use wildcards instead of the full title. For instance, 'Microsoft Flight Simultor*' will pick up any window title that starts with, 'Microsoft Flight Simulator'.
Also something to note is that if the majority of the commands in your profile will be invoked against MSFS, you can set the target for the entire profile through the profile's 'Options' screen. All commands in that profile will then attempt to target MSFS, unless explicitly set in each command (that is. any command that does not target MSFS will need to be set explicitly to, 'Active Window' (or whatever specific window the command needs to target)).
Take a look in the VA help document for more info. Search for, 'Send commands to this target'.
Hope that helps!